Brain Engineering Convergence Research Center
With the recent increase in interest in aging populations and artificial intelligence, there has been a significant surge in the desire to understand the brain. Giant research consortia have been established primarily in the United States and Europe to elucidate the core aspects of the brain and to research methods for treating diseases such as neurodegenerative brain diseases based on this understanding. While existing control techniques are widely studied in fields requiring functional brain reconstruction, such as neurodegenerative brain diseases, their scope is often limited and one-directional. Additionally, they are primarily confined to optical, electrical stimulation, and neural activity monitoring, which restricts their application in functional brain reconstruction.
Our center aims to develop a multi-modal closed-loop system that maintains brain function homeostasis through the regulation of neurotransmitters and neurophysiological signals. By utilizing these state-of-the-art platform technologies, we can provide treatment for various brain diseases ranging from neurodegenerative brain diseases to cognitive impairments by modulating brain circuits. Furthermore, we aim to explore the utilization of this technology in creating new paradigms for medical devices, brain-machine interfaces, or electronic therapeutics.
- Understanding brain circuits based on concurrent processing of electrical and chemical brain signals.
- Development of technology for maintaining brain function homeostasis, previously unachievable with one-way stimulation or drug administration, through research on closed-loop precision control systems.
- Activation of brain engineering research and BMI-related industries through the development of diverse modular-based systems.
- Development of a multi-modal system capable of sensing and stimulating both electrical and chemical signals
- Electrodes and electrical closed-loop systems with 2D/3D composite structures
- Real-time biochemical ion concentration measurement electrodes and chemical closed-loop systems
- Electrode-based drug delivery devices for electrochemical control
- Research on improving the quality of neural signals and signal analysis
- Development of preprocessing techniques for enhancing the quality of chemical neural signals
- Improvement of resolution through neural classification algorithms for electrical physiological activity
- Validation of multi-modal closed-loop precision sensing and control systems in brain circuits
- Establishment of in vitro and in vivo models for system validation
- Validation of precision sensing and stimulation systems based on neural information
- Application of devices with various module combinations for alleviating brain disorders
Ji-Woong Choi
+82-53-785-6311
jwchoi@dgist.ac.kr